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General dickhead. See also Fucker, Asshole, Cunt et al.
That's not my wife you stoopid fuck knucle!
by Izzy Stewart April 08, 2003
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Can be used to describe a person who is generally a dickhead, or used when something goes wrong.
by ~primakat~ August 05, 2005
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A derisory term used to denote a particularly ineffective or annoying person or thing.
Refering to a Person: My fuck! What a useless cunt! I declare him to be an absolute fuckknuckle!

Refering to a thing: I'm not eating that processed fuckknucle Subway calls a sandwich!
by Reginald Whattabone March 01, 2005
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Similar to definition 1 for Fuck Nuts
Specifically a name for somebody you know and despise in one way or another.
"Have you met Wendy's new boyfriend Eric? Man, what a fuck knuckle that guy is!"
by Simonator May 04, 2006
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