He kept hitting me all day but I couldn't do anything because he was a downie.
by Chrissyboi August 24, 2005
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Down-Syndrome Slang
Nasty skit
medical term
Bernard your some downie!?!?!
by grim19 February 25, 2006
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Someone who gets downed a lot in call of duty. originally referred to a person with down syndrome, the definition has changed.
He he, look at that downie."SAM YOUR A FUCKING DOWNIE!"
by bonooch June 06, 2010
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From the term "downer"
someone who brings people down and it a sort of mood-killer.
Josh is happy he got 93% on his test and Mike walks over and shows him his 95%. Mike is a downie.
by Yosh man January 17, 2010
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Downie is a way of referring to a kid with Down syndrome who is a retard and annoys the shit outta people. It is a way of calling an autistic or retarded kid without having to say “the kid with Down syndrome” you can just call him a Downie
Look at Kurt the Downie

Bro did you see that Downie josh? Such a fucken Downie
by Fucken dawg December 09, 2018
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Refering to someone with Downs Syndrome - so really should be "downsie" It is a genetic condition that is increasingly common the older the mother of a child is when she falls pregnant. Downs Sydrome is caused by non disjunction of the 21st chromosome (humans have 23 pairs of chromosomes - each parent supplies 23 chromosomes to the child getting a total of 46) which means chromosome 21 in the mother has not split like it should when making sex cells (gametes) and the child ends up with 3 copies of chromosome 21 compared to the usual 2. Some characteristics of downs syndrome include:

Poor muscle tone
Slanting eyes with folds of skin at the inner corners (called epicanthal folds)
Hyperflexibility (excessive ability to extend the joints)
Short, broad hands with a single crease across the palm on one or both hands
Broad feet with short toes
Flat bridge of the nose
Short, low-set ears
Short neck
Small head
Small oral cavity
Short, high-pitched cries in infancy

Sufferers of Downs Syndrome are ussually smaller than their normal peers and their physical and intellectual development is ussually slower.
"He looks like a downy."
"Her brother is a downy."
by [skorpion] December 09, 2004
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