to be deffenderferred means to have your Facebook status, pics, links, etc. ruined by the comments of one person, whom is not liked by many, to which NO ONE else posts a reply or comment; or the status thread that had been ongoing comes to a halt once this certain person comments.
Miranda and Dee were commenting on the most recent update from the WJJO fanpage when it all of a sudden it was deffenderferred, stopping all conversation.
While our lifespan is the number of years we will live, our healthspan is the number of healthy years we will have and our sexspan is is the number of years we will continue to be healthy enough to continue having an active sex life.
A lighthearted reaction upon receiving disappointing news of some sort. Usually something that isn't a particularly a big deal, esp. when it primarily affects someone else - sort of a mild schadenfreude. Sometimes doubled or tripled, and possibly said in a sing-songy voice for added comedic effect to imitate a muted trumpet, which is how the meme originated.