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defo = deformed
'Defo' can be used in a variety of ways. It can be used jokingly, in moments of indignation, and even in a casual setting.
1. Ew did you see that deer? It's so defo...
2. Come on Jill, let's hang out! Don't be defo
3. I throw my hands up in the air sometimes saying A-Yo I'm a defo!
by WhatYou'veEarnedHereTonight March 06, 2011
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A bunch of white kids trying to be ghetto while eating donuts and doing calculus homework outside of Casey's in the either extremely frigid or unbearably muggy air, about 15 miles from Madison, WI.
Teenage DeFo resident:"DeFo fo sho!"

Non-DeFo resident: "Uh, no."
by Juliferie January 19, 2007
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food and desert combined with desert as the first meal
That was some good defo man! I want more!
by September 15, 2020
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