D.F.I. Share definition Flag Drug F*cked Idiot-a drug user-use to refer to anyone who is totally drug effected or DRUG F*CKED "That guy she's seeing is a total D.F.I." D.F.I. by whoozawhatzit March 2, 2008 0 0 Get merch Get the D.F.I. mug. Buy Now — $32.95 See more merch