D.F.I.

Drug F*cked Idiot-a drug user-use to refer to anyone who is totally drug effected or DRUG F*CKED

"That guy she's seeing is a total D.F.I."

by whoozawhatzit March 2, 2008

D.F.I.

Different Fucking Idea- when a plan changes- the original idea is Spanished and the cry of "D.F.I." goes out.

" D.F.I. on that! We're doing something else."

by Seaguller August 14, 2009