the longing for something unattainable(could be a person or inhuman object) to the point of near insanity.

inspired by Edward cullen of the twilight seires
a: dude my girl wants to go all the way, but i took a vow of chastity

B: dude you've got some serious cullen syndrome
by Logan-943 May 15, 2009
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N. When you find someone so attractive, they could say and do the creepiest things to you, but you won't realize it because you're blinded by their beauty.

I.E the effect that Edward Cullen from the Twilight series has on the main character, Bella.
Girl: OMG You're amazingly hot.
Guy: I watch you in your sleep, and might beat and kill you for the hell of it.
Girl: You're so handsome. I love you.
Guy: Damned Edward Cullen Syndrome

Guy 2: Has anyone ever told you you look like a model?
Girl 2: If I ever see you flirt with another girl again, I'll castrate you.
Guy 2: *stares at breasts*
Girl: Damned Edward Cullen Syndrome
by Lakehurst June 16, 2010
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