This is a genetic abnormality that does not have to do with being gay, lesbian, etc. This abnormality is seen when the XY or XX chromosomes have more than the usual X and Ys. This can lead to infertility in males or females and physical traits not normally of that sex. For more information, check the page on biology. about. com about Sex Chromosome Abnormalities.
Sex-chromosome anomaly (abnormalities) are a result of chromosome mutations.
by Phoebe Jones May 10, 2016
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weed so strong that once inhaled you feel the retarded effect that an extra chromosome has on the brain. In many cases this cannabis can and will make you shit your pants without any warnings. Dumbed down this weed is described as the bees knees if the bees knees were 10 piece mcnuggets straight from God's lotion sack.
Woah bro (random grunt noise) this Extra chromosome weed got me absolutely zoinked.
by master doodoo poo April 2, 2019
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Something that doesn't exist
There's NO such thing as a sex-chromosome anomaly. Being gay, or lesbian isn't a disease, or a deformity, no matter what people say, there's no need to make excuses for why people are gay, especially if you're truly proud to be gay or lesbian
by Ron tha Don June 30, 2014
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A man's ejaculate, warm and creamy, ready to be consumed by his sexual partner. So-called, because of the 23 chromosomes of DNA contained in the sperm.
Man, that girl I took to dinner last night was hot. She had some of my 23-chromosome pudding for dessert.
by perverted_one June 6, 2007
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The boost chanelb in the youtoobs soobscribe today please chanelb is made by man or child Sanchez who only has 45 chromosomes. In his free time Sanchez likes playing mine craft and dressing up in his Asian war helmet. His subs are called chromi homies. The Channel is called 45 chromosome gaming
My chromi homi Sanchez is the creator of 45 chromosome gaming.
by Bauxite November 29, 2017
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idiom/adjective phrase: to be mentally deficient in a very noticeable manner.

Etymology:

From the fact that many cases of mental retardation involves having an abnormal number of chromosomes.

Notes:
Funnily enough, means the same thing as "to have a couple extra chromosomes". "To be short a couple chromosomes" is perhaps a more natural way of expressing the idea as it plays to the human intuition that "more is better" and also because it is very easy to imagine how someone without the normal number of chromosomes could turn out retarded; however, "to have a couple extra chromosomes" may actually be more accurate in most cases. The most common genetic cause for mental retardation is Down's syndrome, which actually involves having more chromosomes than the normal person (a third copy of chromosome 21, to be precise).
I asked Zoe why her cousin was such a manchild, and she said, "Oh, he's short a couple chromosomes."
by Choosy Floozy November 24, 2019
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Son of a Y-chromosomed dog!
The Y-chromosomed dog had 6 puppies.
by PigeonSlayer February 7, 2019
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