Anal handshake Share definition Flag To forcefully place your opened hand between a friends buttocks when they are in a vulnerable position. I was just about to sink the 8 ball when jeff raced up behind me and gave me an anal handshake. Anal handshake by Bogan King October 9, 2008 0 0 Get merch Get the Anal handshake mug. Buy Now — $32.95 See more merch