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Heavily congested freeway that runs generally through the west-central part of Los Angeles, California.

(There are also interstate highways with this number in Washington & Oregon, but the California version is the most famous.)
The gridlock on the 405 is legendary throughout the country.
by Zalis December 08, 2003
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Jul 26 Word of the Day
Noun: a friend who is usually only called upon by a friend when a more primary/prominent friend is unavailable.

Taken from the term β€œsecond string” in an athletic competition situation. In football, if the star quarterback gets injured during a play, the second string is called off the bench to replace him/her. A β€œSecond String Friend” is essentially benched until needed, if ever.

Synonyms: Plan B, Second Choice, Secondary Friend, Benched Until Needed
I got a call from X the other night. She had an extra ticket to a concert she bought for a friend, but they couldn’t make it so she called me to ask if I wanted to go because I am her Second String Friend.
by Deus-ex-machina August 26, 2020
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2
1. Interstate 405, which runs through southern California and Los Angeles.

2. called β€œthe 405”, central Oklahoma and especially Oklahoma City. So called for its area code.

3. 405 "Method Not Allowed", an HTTP error code.
1. The 405 has archetypal bad traffic.

2. Back in the 405, we used to have it so good.

3. Um, John, why is there a big 405 on the screen?
by tangles10 September 12, 2010
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4
from the http error message 405 "forbidden"

Often means "over the line"
Stop man, that room is 405

You take that back fo' that was 405
by Da Zeg January 08, 2005
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5
the most poetic 3 digit number ever. It's perfect imagery and makes you think of those moonlit nights when you just feel so tired that you feel so great and the lights are just perfect.
by bengibbard March 21, 2009
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6
a cool bus that drives around town and picks up ppl
here comes the 405

here comes the bus 405

man that 405 is cool
by 405 September 13, 2004
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