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1. To own someone in something they're good at.

2. Also an item in most video games that gives you an extra life, so when you die, you can continue your game.
1. Josh went up to Jon and challenged him on Guitar Hero 2, Josh won. "Oooh! He just 1-up'd you!"

2. "Grab the 1-up! You only have 1 life left."
by 7even0h7ev August 26, 2007
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2
An extra guy. You'll need a lot of these if you suck at a game.
by e-vis November 05, 2003
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When you and or one of your classmates get a boner in class, and are called up to the front by the teacher, one must scream 1up and a friend will take your place at the front instead to save you from embarrassment.
*Mrs. Gibbons calls up Tony*
Tony proceeds to say loudly: 1up!
Eric then volunteers to take Tony's place and saves him from embarrassment.
by D-bag69 February 11, 2018
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4
literally means "get a life". from the super mario brothers when mario gets a extra life.
person #1: i dont have a girlfriend because i paly video games all day.
person #2: 1up motherfucker.
by !!!!!!!!!!!!!! May 23, 2007
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6
1. (v) when somebody just tries to over power things you say to rule the conversation, or plainly, the motherfuckin world so theyre just hella doper than your ass for some stupid ass reason..

2. (n) the knock who wont stop thinkin theyre the shit yadida.
1. (v) Joe Shmoe: Man, look at my fucking RAZR, its silver!
John Doe: I have a RAZR, too. But hey! Mine is gold!
Frank: John, quit trying to 1up. You can't rule the world, dumbass.

2. Jane Doe: My outfit shits on your outfit. All of my outfits stay shittin on everybody outfit right quick. Look at me, model status tho. Deeeamn, who's that celebrity. Oh, me!
Diana: Jane, shut the fuck up you 1up.
by 1UPYOURFACE August 25, 2007
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7
In supplier terminology, a secretive name for the common psilocybe cubensis mushroom.

It is usually used only to be discrete (e.g. when texting or talking in public); sometimes to make yourself feel cool for using unique terminology...
daGDnig: how much 1up dis kid want cuzz?

Brian: he want a lb but i talked him down 2 a qp cuz he aint hav da cream.

daGDnig: dam u done it already? thas wassup.
by daGDnig May 17, 2010
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