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mother fucker 

Is a noun that can represent any person place or thing.
1. That mother fucker owes me money.
2. Your party sux. This moter fucker is boring.
3. Im hungry as a mother fucker.
4. When i hit you, that mother fucker is gonna hurt.
5. Im broke like a mother fucker.
mother fucker by Anonymous March 29, 2003

Beans and motherfuckers 

A disgusting mix of Lima Beans and Ham, as made for the United States Military in the form of C-rations and MRE's (MRE= Meals Refused (by) Everyone)

bitch ass motherfucking cockface 

Steve: I had sex with your mother.
John: You little bitch ass motherfucking cockface!

motherfucked

To be severely fucked, used especially when describing the state of a device, piece of software, location, establishment, or a situation.
I think my laptop is motherfucked.

The IRCd: it's motherfucked.

This hotel is motherfucked. There's a dead hooker in the bathtub and I'm pretty sure I saw some bedbugs.

Spidy it's motherfucked.
motherfucked by echicken June 13, 2011

run like a mother fucker 

to run as fast as you can
Tony: Shit, its da cop!

Me: Run like a mother fucker!

head to the motherfucking desk 

1. What you use to respond to an idiotic question when "*head to desk*" or "*facepalm*" just isn't strong enough.

2. What you say when you've done something dumb when you were tired/inattentive/drunk.

3. What you do whenever Sarah Palin appears on the telly.
Mouthbreather Martin: "Can vegetarians eat animal crackers?"

Awesome Amanda: "*head to the motherfucking desk!*"