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have the shits 

To have diarrhea. To go to the bathroom and evacuate your bowels in liquid form.

It can also be used if you have a lot of belly pain and have to go constantly to the bathroom for number two.
Poor Mary, she has the shits.
My cat had the shits last night.
I think I have the shits.
have the shits by NAjA November 26, 2013
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weed shits 

weed shits generally happen after a long night of blazing and trying to stem the tide of munchies. As we all know the best food to deal with said munchies is junk food which is barely digestible. Therefore the next morning about 90% of the food that was consumed is forced out the opposite end that it went in.
Oh man i just had the worst case of the weed shits in my life
weed shits by ajax2220 October 31, 2009

sodexo shits 

after eating sodexo's college food, its when your ass lets loose the second that you sit down and feels like your shooting fire out your ass

typically a daily occurring incident if you are on a meal plan. tend to happen all semester, unless you eat real food or go home to eat mom's home cooking
after i ate lunch today in the cafeteria, i got the sodexo shits

shit to end all shits 

Something you say after taking a huge shit, where it feels like it's the biggest one you ever took in your life.
Holy crap! I took the best dump right now! It was the shit to end all shits! If I died right now, I'd be happy , the shit was THAT good!
Of or relating to a kid who craped his pants at newsome high school in the year 2008-2009.
Oh no i just shit my pants! I am shitsco now.

Sir ShitsAlot

Someone, usually a guy, who has dirrhea. Especially after Taco Bell.
Where's sir shitsalot at?

tim?

Yeah.

at taco bell again.
Sir ShitsAlot by awesomeman134679 December 28, 2010

Boner Shits

When one suffers from the adverse side-effects (mostly bowel related) of Viagra.
Oh damn Clara, I have the boner shits.
Boner Shits by theface2277 July 20, 2013