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Marijuana Overdose 

While there has not been any reported fatal case of marijuana overdose (marijuana overdose being the primary cause of death, not relating to a mix of drugs or a prior medical condition), a person can most definitely produce very unpleasant and potentially serious side effects to the drug when consuming very high quantities of THC at a time.
This is very possible when eating THC laced content (i.e brownies, cookies), rather than smoking it (you only get 10-15% of available THC when you smoke a blunt).

Side effects include increase in heart rate/ blood pressure, difficulty breathing, increase in body temperature, disorientation, nausea, decrease in muscle coordination.

Other more frightening, psychological/psychosomatic symptoms include hallucinations (i.e tunnel vision), paranoia or terror, panic attacks, loss of "self", loss of time perception, short-term memory loss, and slurred speech. It is important to seek medical attention if breathing becomes shallow and slow or if a person loses consciousness. Side effects also depend on the individual, the amount consumed, and an individual's tolerance level.
"OMFG, I ate too many weed brownies, I think I'm having a Marijuana Overdose."
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Nigger overdose 

The only known marijuana overdoses from less than 30 black people smoking a gram of pot steams and seeds. They start saying " IM FEEEEEELING IT DAWGS!" then have to go to the hospital but on the way get A Niggery pulled on them for their car radio and chain.
The biggest known Nigger overdose was when tyronne purchased a gram of weed for tree fiddy and shared it between a gang of 70.
Nigger overdose by Tyronne Biggums November 11, 2006

Water Overdose 

Means "drown" but only for ~non-basic bitches~
Holy shit, Trevor just water overdosed while he swimming in pussy
Water Overdose by King Nipple September 18, 2018

Rhoto overdose

The act of smoking weed and then using Rhoto's eyedrops, and repeating the process. By doing such, you get an overdose of Rhoto's and the slight burn that usually burns so good is now painful.
Man... Last night I smoked so much weed i had to use Rhoto's three times in like 4 hours. I definitely had a Rhoto overdose.

COD Overdose

When someone plays Call of Duty too much online, they begin to start replacing the letter e with an a.

Bob: Man I owned to the fehce (face)
Ronny: dude you got a COD overdose
Jim walks up
Jim: I play Call of Duty all deh (day)
COD Overdose by COD ALL DAY March 9, 2010

Viagra Overdose 

Much like other drugs, Over use of Viagra (Especially in men ages 70+) can give you a heart attack. This is what we call a Viagra Junkie
Did you hear about the guy who died of the Viagra Overdose?

They couldn't shut the Casket!
Viagra Overdose by CMaWL May 14, 2016

Birthday Overdose 

A REALLY old person. Someone who has outlived the enjoyment in their lives.
Look at this wrinkley old broad. How is she managing to stay alive? Poor lady is suffering a birthday overdose over here..