little sister

the one that made your life HELL for years
hey, I really like your little sister
by Friday the fortnut November 05, 2018
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Little Sister

A younger female sibling that can be annoying as hell and you probably fight a lot with. But no matter what's going on, she will always be by your side wether in good or hard times and help as much as she can to make you feel better when you are down.
Although my little sister makes me going crazy literally all the time, she's the best one of them all
by AkaLee November 21, 2016
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Little Mouse

The sperm that penetrates the egg.
Kid: Where do babies come from?
Mom: When the little mouse eats the cheese, a baby is born,
by DJ URL October 15, 2015
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little guy

street slang for a roxicodone 30 mg instant release pill.

slang for an roxy on long island, new york.
user- "lemme get a little guy"
dealer- "i got u..20 bills"
by thatOCguy February 23, 2010
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Little shit

a small blonde biddie from the Hamptons who never shuts up.
Rachel is bugging me to smoke again, what a little shit!
by LT Shanteezy May 03, 2011
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little debbie

A female that allows a male to ejaculate inside her.

A pun off the snack cakes of the same name that have cream filling.
One thing led to another and next thing you know: she is my little debbie.

I little debbied her.
by Troublecitrus May 10, 2012
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Little girl

A young girl under the age of 13 both annoying and creepy and knows how to get her way
Olivia just turned 12 she is such a cute little girl
by Lalallalalalala January 21, 2018
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