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Non-Responder

A non-responder is an individual that you attempt to contact but he does not respond.
I tried to contact them but they don't respond. Therefore he's a Non-Responder.
by Bailmaninmo December 14, 2018
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Thirst Responder

Somebody who drives a firetruck full of beer and/or soda to quench the thirst of partygoers and neighborhood rockstars.
The thirst responders rolled up in Ladder 419, started serving ice cold drinks and the party got started.
by Tapped419 June 22, 2023
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First Responder Moment

A First Responder Moment is when a first responder addresses a traumatic situation humorously by saying something even more messed up, only to realize it was just their real mental state slipping through that they've been trying to ignore.
Officer 1: Hey man, that body is still somebody's son, wouldn't you feel bad if somebody said that about your family?
Officer 2: Eh, well, womp womp, I don't really feel much of anything anymore.... Oh shit, I just had a First Responder Moment
by Drella_Fella September 6, 2025
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It's Not Responding

Gamer 1: Did you lose again?
Gamer 2: It's not responding.
by Ed Sky December 19, 2019
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Lean Mass Hyper-Responder

The term "lean mass hyper-responder" was coined by software engineer David Feldman on July 3, 2017 while posting in his low-carb diet blog: "Cholesterol Code." The blog post called "Are you a Lean Mass Hyper-responder?" quickly circulated through the low-carb community.

As background, the original term "hyper-responder" was already used by dietary professionals for years prior to Feldman's blog post. And in dietary literature, a "hyper-responder" is someone who adopts a low-carb diet, then experiences dramatic cholesterol elevation. So when Feldman wrote his 2017 blog article, he co-opted "hyper-responder," and crafted his new term "lean mass hyper-responder" to describe what he believes is a metabolically unique sub-set of all hyper-responders. Specifically, some hyper-responders begin a low-carb diet while already in possession of a very lean body mass. And yet in spite of this, they still --quite counter-intuitively-- respond with extreme cholesterol elevation. Additionally, these subjects experience a marked decrease in triglycerides, while exhibiting excellent metabolic health. The entire phenomenon defied a long-standing metabolic theory called "The Lipid Energy Model," presenting a scientific conundrum for Feldman.

Feldman believed that all this was a significant observation worth exploring. And his efforts eventually led to a 2023 research project called "The Lean Mass Hyper-Responder Study" led by Dr. Matthew Budoff and Dr. Nicholas Norwitz at Lundquist, UCLA.
IN A SENTENCE: "Steve has always been a tall, skinny, beanpole of a guy. And then when he went on the carnivore diet, he was still skinny, but his cholesterol went through the roof. His doc said that overall he's pretty healthy, so he might just be a lean mass hyper-responder."
by Innocent Byproduct December 13, 2023
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