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Synonomous with damn, darn, etc. Used as an expletive.
"You spilled coffee on your shirt."
"Well, biffle!"

"You don't have a date for prom?"
"No, I've been biffled!"
Biffle by Kitty11 May 25, 2008
Biffle
(Bif-ull)

When a man or woman gives 2 dirty sanchez's to there partner and licks the defication off there partners chest, then deficates in the girls vagina and has sex through it.
Biffle by Drew Schaetz October 16, 2008
The definition of biffle is Morgan. Biffle is someone you love so much. And you can only have one. Biffle means Best intense friend for like EVER!!!
I love my biffle, Morgan<3
Biffle by JessicaaLee May 14, 2011
An unspoken bond between friends who share everything together, and do everything together making them appear attached at the waste. Who are best friends through thick and thin.
Duke and Melissa-Joe are always seen together and appear as Biffles among their group of friends.
BIFFLE by Landscape Duke July 7, 2011
A Best. Friend. For. Life. A super awesome friend that totally gets you.
His biffle was having a bad day so he brought roses to lift her spirits.
biffle by biffles. are. cool. October 13, 2011
To make someone your best friend for life. Forming a strong, friendly connection with someone.
I met Tina last night and I totally biffled her!
Biffle by meowzilla July 31, 2012