verb - To botch, bungle, or otherwise screw up in the heat of the moment, often out of a sense of panic.
"Man, our TV satellite signal went down right before kickoff on Sunday, so I freaked out and climbed up on the roof. I ended up knocking the dish off its mount and down two stories onto the diveway - a real flush the mouse situation on that one."
by shibby917 March 27, 2024

A phenomenon describing when you flawlessly survive gastrointestinal/stomach pain after eating something that is supposed to induce it.
Jake has had a 2-year history of successful garbage flushing, no matter what kind of chili sauce he takes!
by Pseudonymous Johnson June 19, 2020

BOB: Are you alright in there, Jeff?
JEFF: Leave me alone, I'm flushing the goldfish.
MABEL: I feel so rough after last night.
KAREN: Me too. I was flushing the goldfish until three in the morning.
JEFF: Leave me alone, I'm flushing the goldfish.
MABEL: I feel so rough after last night.
KAREN: Me too. I was flushing the goldfish until three in the morning.
by WhatTheYeet September 11, 2020

Losing badly, doing something terribly, something almost tragic. As heard on the Tony Kornheiser Show.
He went 0-4 last night. He really flushed the mouse. They flushed the mouse when they lost by 31 points. He really flushed the mouse with his date when he got too drunk.
by Schmeckle33 March 27, 2024

when a mothafucka walks up in a fast food restaurant uses the restroom and then leaves without the purchase of any food item.
did those people just come in to use the restroom?" "yeah they just did a flush puppy on their asses.
by brown boy ni66a July 26, 2010

When one, in a fit of anxiety and unsure of the best next steps, makes a rash an ill-advised decision leading to a bad outcome. Originally conceived and made famous on the Tony Kornheiser Show.
I wasn't even sure what state Oakland was in, but I only had two more minutes to submit my bracket, so I picked Kentucky to win. Man, I really flushed the mouse on that one.
Tony: I didn't know what to do with this dead mouse. So, I thought, "I know! I'll flush the mouse."
Michael: Oh, no.
Tony: I didn't know what to do with this dead mouse. So, I thought, "I know! I'll flush the mouse."
Michael: Oh, no.
by xSD-305x March 27, 2024

Someone who gets very upset when a prior person did not flush the toilet, resulting in them having to flush it while pissed off.
"Who used the toilet and didn't flush again. It pisses me off when I have to flush for you." resulting in the act of an angry flush.
"You fuckers didn't flush the toilet again. This is a work place and I am not your mother, so FLUSH the damn toilet so I don't have to angry flush for you.
"You fuckers didn't flush the toilet again. This is a work place and I am not your mother, so FLUSH the damn toilet so I don't have to angry flush for you.
by T.S.A - Toilet Safety Admin. April 19, 2014
