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A ho is a girl who spends her time with people who don't care about her. This includes more girls than one would think, but is a very useful definition.
You can tell that girl is nothing but a ho by the way she hangs out with all those basketball players.

"Fellas gotta quit treating these nice girls like hos, and these hos like nice girls.
Ho by Craig la Cocina July 17, 2006
Related Words
hoe homework horny HOT Holly Hot Topic Hope ho Homosexual hotpocket
ho by VVoody September 11, 2003
Ho by ZDavey May 1, 2009
A variation on the word "whore", stemming from a regional North American pronunciation of the same word.

Cited by the case U.S. v. Murphy in the 7th Circuit Court of appeals on page 2, footnote 1
"The trial transcript quotes Ms. Hayden as saying Murphy called
her a snitch bitch “hoe.” A “hoe,” of course, is a tool used for
weeding and gardening. We think the court reporter, unfamiliar
with rap music (perhaps thankfully so), misunderstood Hayden’s
response. We have taken the liberty of changing “hoe” to “ho,” a
staple of rap music vernacular as, for example, when Ludacris
raps “You doin’ ho activities with ho tendencies.”
"why do you think you take a ho to a hotel?
Hotel everybody, even the mayor
Reach up in tha sky for tha hozone laya
Come on playa once a ho always
And hos never close they open like hallways
An heres a ho cake for you whole ho crew
an everybody wants some cuz hoes gotta eat too"
--From "You a Ho" by Ludacris
ho by eltacote May 6, 2005
One rung below whore on the social ladder.
Ho by SiliconHero April 24, 2003
slang term for hot girls who are sluts
She just had sex with 8 guys...at the same time!, what a ho!
ho by Sergio April 5, 2005