Shiz Share definition Flag 1. Sure or For Sure, most likely derived from "Fo' Shiz" or "Fo' Shizzle" 2. Shit. Most likely derived from "Shizzit." Marisa: Hey, are you going to Battle of the Bands? Alison: Shiz man. "What a piece of shiz!" Shiz by Alison May 16, 2005 0 0 Get merch Get the Shiz mug. Buy Now — $32.95 See more merch