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The potent concoction of Rohypnol and Mountain Dew. Commonly used in southern states to knock fellow ancestors unconscious.
“Hey Sam cook me up some more Alabama NyQuil! I think Sister Sarah is waking up!”
by Bobby Windchime May 3, 2019
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Colombian NyQuil

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Instead of swallowing an ambien for sleep, you crush it into a nice powdery line and snort it for instant effect.
Guy 1: Hey man I have to go to sleep like right now. I have to be up at 6 for work.

Guy 2: Do you want a shot of whiskey to fall asleep faster?
Guy 1: I’m way ahead of ya. I’m taking a Colombian NyQuil . Be out in a minute
by Les Carroll August 31, 2020
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texts from last nyquil

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the act of texting after comsuming a large amount of Nyquil.
"You were crazy talking last night. Do you remember what you were saying?"

"No, they were texts from last nyquil."
by mister j October 27, 2009
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“Used specifically for putting a person to rest permanently or temporarily, the choice is in the user’s hands of this fabled technique. People that use this technique suffer severe or fatal injuries after if their bodies cannot handle it’s immense power.
Person 1: Did you hear what happened to Andrew?
Person 2: No, what happened?
Person 1: Mikey hit him with the “Fabled NyQuil” and knocked him into the sun.
Person 2: Poor Andrew, I bet he’s probably waiting in line at the Heaven Gates.
The Fabled NyQuil is a technique of which is forbidden in some places due to it’s destructive nature to those who wield it and those who are attacked by it.
by Junohh January 3, 2021
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Sperm, seamen, cum, and the list goes on
23:32 fatbottmedgal: I can't seem to find the NyQuil... *pout*
23:33 chains1872000: i have some white nyquil to inject in you....
23:34 fatbottmedgal: mmmm oh is that so *blush*
23:34 chains1872000: hehehe, yes ma'am
by alester starr November 1, 2008
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When you can’t fall asleep so you bust a fatty in order to go to bed
Dude last night I couldn’t fall asleep so I took some homemade nyquil!
by Papafluffdaddy April 22, 2018
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