The man who saved comedy. Jewish Canadian-born actor responsible for films such as Superbad, Knocked Up and Pineapple Express.
by SergeantNOSHIT March 30, 2009

1. The creator/writer/cast member of Family Guy and some other stuff.
2. The cutest, funniest and most talented television personality of the 21st century.
3. 3rd greatest living voice actor (Dan Castenella is the 2nd and Billy West is the 1st)
4. My Hero and Crush.
5. Seth MacFarlane Syndrome; a slang term for people who are stupidly modest.
2. The cutest, funniest and most talented television personality of the 21st century.
3. 3rd greatest living voice actor (Dan Castenella is the 2nd and Billy West is the 1st)
4. My Hero and Crush.
5. Seth MacFarlane Syndrome; a slang term for people who are stupidly modest.
Look up Seth MacFarlane on youtube and watch a few vids, then maybe (if your not crazy) you'll like him
by simpuramafampark August 5, 2009

by sex monster's left pussy flap October 2, 2021

by Urmom;) May 26, 2018

by charleegrace23 April 17, 2020

This person is like the fierceness of Tyra Banks, RuPaul, Kimora Lee Simmons, Kim Kardashian, Lady GaGa, Beyonce, Christina Aguilera, and Rihanna all put together in one! and that is Seth Tackling
by sethat90 June 16, 2010
