An extremely intelligent person who doesn't deserve hatred. Please keep the negative comments about Down syndrome people to yourself. Thank you
by alay.s May 5, 2016
Get the Downsyndrome mug.John: Yo I just smoked another bowl. That makes 180!
Mike: Yeah well I drank a 30 pack of Corona, now I've got the sit downsies.
Mike: Yeah well I drank a 30 pack of Corona, now I've got the sit downsies.
by Sandwich Mike December 22, 2009
Get the Sit Downsies mug.Related Words
Downsiy • downsyndrome • downsy • downside • Downsey • downsie • downsizing • downsyndrick • Downside equity • downside of advantage
When your life is turned upside down and crap really starts hitting the fan due to a job loss caused by downsizing or out-sourcing.
"Do you see how John has lost control and has really been"rusting his windpipe"(drinking a lot) since his life has been turned upside-downsized after losing his job?
by Maat9999 June 16, 2010
Get the Upside-Downsized mug.A word meaning that you are "down" to do something;
You think something is a good idea, and you want to participate
You think something is a good idea, and you want to participate
by jorman1 April 23, 2011
Get the downsies mug.Refering to someone with Downs Syndrome.It is a genetic condition that is increasingly common the older the mother of a child is when she falls pregnant. Downs Sydrome is caused by non disjunction of the 21st chromosome (humans have 23 pairs of chromosomes - each parent supplies 23 chromosomes to the child getting a total of 46) which means chromosome 21 in the mother has not split like it should when making sex cells (gametes) and the child ends up with 3 copies of chromosome 21 compared to the usual 2. Some characteristics of downs syndrome include:
Poor muscle tone
Slanting eyes with folds of skin at the inner corners (called epicanthal folds)
Hyperflexibility (excessive ability to extend the joints)
Short, broad hands with a single crease across the palm on one or both hands
Broad feet with short toes
Flat bridge of the nose
Short, low-set ears
Short neck
Small head
Small oral cavity
Short, high-pitched cries in infancy
Sufferers of Downs Syndrome are usually smaller than their normal peers and their physical and intellectual development is ussually slower.
Poor muscle tone
Slanting eyes with folds of skin at the inner corners (called epicanthal folds)
Hyperflexibility (excessive ability to extend the joints)
Short, broad hands with a single crease across the palm on one or both hands
Broad feet with short toes
Flat bridge of the nose
Short, low-set ears
Short neck
Small head
Small oral cavity
Short, high-pitched cries in infancy
Sufferers of Downs Syndrome are usually smaller than their normal peers and their physical and intellectual development is ussually slower.
by [skorpion] May 28, 2006
Get the downsy mug.A person, generally from the eastern hemisphere, who has been stricken with an extra twenty first chromesome given to them by their unloving mother. This extra inconvenience is refferred to as "Trisomy 21," and often forces the "downsy" to live a life working behind the scenes of carnivals (out of the public eye) and eating everybody's cookie dough.
Though I commited the crime, I blamed my downsy cousin and got him put behind bars where he belongs.
by Julio Sanchez September 19, 2005
Get the downsy mug.A negative word used by shallow and inconsiderate people to describe themselves or others when they a) look stupid or b) act stupid, because they think looking and acting dumb is a trademark sign of Down's syndrome. Used by people who have never met someone who actually has Down's syndrome, and who are ignorant of and insensitive to a serious condition.
Cassie: Ewww! I look so downsy in this facebook picture, haha. I look sooo gross! I'm untagging myself!
Anne: Um, you look fine.
Rob: Yeah, shut the fuck up. My sister has Down's syndrome.
Anne: Um, you look fine.
Rob: Yeah, shut the fuck up. My sister has Down's syndrome.
by Rob and Sophie January 6, 2010
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