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to slack off after a period of doing a reasonably acceptable job in an activity.
athletic kid: come on! only 5 more miles!

fat kid: fuck that!

athletic kid: dont let up on me now!
let up by domiyan December 4, 2012
Related Words

Buckle Up Buckaroo 

Metaphor for: "Get ready cause some crazy shit's about to go down!" or "Get ready for a wild ride!" or what you say before the shit hits the fan.

History: Derives from old cowboy rodeo phrase, as a reminder when riding on a wild bull or bucking bronco.

Pop Culture: A favorite phrase of Caitlyn Jenner on South Park, which is then usually followed by someone getting accidentally killed by her.
Guy at bar asks Caitlyn Jenner: "It should be an interesting election this year huh?"

Caitlyn sips her drink and fiendishly replies: "Buckle up buckaroos."
Buckle Up Buckaroo by ZorkMuse December 15, 2016
The phrase "size up", usually used in arguments, essentially means to "stand up and fight"
"Yo, no long talkin' b. Either size up or nize up"

In other words...

"Hey man, I don't want to do this long talking business anymore. Either stand up to me and let's fight, or shut up."
Size up by suwayy March 26, 2017

KuT U Up 

An awesome band who went on the Pop disaster tour and were known as the least sober band of the tour. hau hau
KuT U Up's lead singer, Chris Cote was branded an his ass by Billie Joe Armstrong from green day
KuT U Up by Kerplunker45 August 15, 2004

head up your ass

1. The condition of being absolutely oblivious to surroundings 2. Acting like an asshole
1. "You didn't know the pope died? You have your head up your ass, dude"
2. "You told everyone you had sex with my mom!? You have your head up your ass, dude"
To get your hair outline fixed. a shape up(usually for black people hair)
"I'm about to go get an edge up."
edge up by Uzo June 25, 2005