Speedball 

A mixture of heroin and cocaine administered intravenously. This combination offers the best of both drugs. The lady (coke) gives you a rush of intense euphoria followed by the soporific effects of your boy (heroin), thus effectively eliminating the anxiety and depression that follows when shooting up cocaine by itself.

Me: I've never smoked crack but I've done speedballs.

You: You're fucking kidding me, right? You've shot up coke and smack? I'm breaking up with you, Dumbass.

Speedball by kookaburra March 17, 2015

Northwest Speedball 

The Northwest (USA) version of the classic speedball douse.

To combine espresso coffee shots with marijuana hits in rapid succession.

Shane and Rick were local coffee shop parking lot doing Northwest Speedballs before they headed for the local rock show in downtown Seattle.

Northwest Speedball by Lodoc October 24, 2009

Suburban speedball 

A recreational drug combination used by suburban housewives. Instead of the traditional cocaine-heroin mix, this speedball is usually vicadin, valium or oxycodone with a latte chaser.

After a hard day of shopping at the mall, Diana settled down with Oprah and a Starbucks-Valium suburban speedball.

Suburban speedball by gjn413 February 13, 2010

Kentucky Speedball

An injected mix of methamphetamine and oxycontin.

That chick they found in the port-a-pottie OD'd from a Kentucky speedball.

Kentucky Speedball by PoppyMann July 5, 2007

green speedball 

A large joint and a Limeade Mountain Dew® Kickstart™

Start your day with a green speedball for a productive burst of energy.

The green speedball is the productive stoner's answer to hating coffee.

Built for people with a relatively tame substance-abuse pattern, the green speedball will nevertheless test it.

green speedball by Auloi November 29, 2016

Slav speedball 

The state you are in after snorting a line of blow and ripping a bong.

- He died from speedball!
- Have you heard of slav speedball?
- No, how does it compare?
- It's not as deadly and soul-crushing but it's a lighter version of an inhibiting, 'downer' drug and a hardcore accelerating stimulant - blow and weed.

Slav speedball by matopato July 11, 2021

Speedball 

A speedball is NOT heroin mixed with cocaine. Speedballs don't contain cocaine or Crack. A speedball is heroin mixed with speed (Amphetamine, Ethylamphetamine). It's in the name, stupid. Speed is the Speed part and Heroin is the Ball part. Heroin makes you sleepy and Amphetamine makes you awake and energetic. Don't do heroin! Stick to Kratom! Also, don't do fentanyl. You can dissolve Amphetamine and Heroin in DMSO and put it on your skin and it goes right inside your body. The speedball can kill, but if you survive, you can get super high.

I mixed Heroin and Amphetamine in DMSO and poured it on my skin. It ended up in my bloodstream and I got super high. This is a great speedball.

Speedball by CognitiveFuel January 12, 2023