An exclamation added to the end of a sentence... e.g. when you hate flood pants but then you realize how effective they really are.
"My feet are soaked, but my cuffs are bone dry! Everything's coming up Milhouse!"
by Legit not a troll February 19, 2018
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When all possible choices or venues have been exhausted with no favorable result.
I tried to find the DVD at Wal-Mart, Best Buy, Circuit City, even at the pawn shop, but everything's coming up Milhouse.
by herphosmanolin August 21, 2008
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When everything in life is serendipitously permuted, everything comes up, Milhouse.
"A wise man once told me that there are only two...maybe three Milhouses...in a lifetime!"

Philly D - "So, I got the job that I interviewed with last week, today!"

Jessie S - "I'm glad that things are going good for you."

Philly D - "That's not even the half of it! Remember, Caroline, the girl who makes gold teeth?"

Jessie S - "..."

Philly D - "She let me in her shit gun!"

Jessie S - "shit gun?"

Philly D - "Ahhh, that's call waiting. Can you hold a sec? It says publisher's clearing house."

Jessie S - "You just went on a three day Milhouse!"
by DrDingDong March 27, 2019
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