Cissy Share definition Flag A slur against Cis-gendered people normally by Trans people made from a combination of the word 'Sissy' and 'Cis'. The plural form is 'Cissies'. You cissy cis-gender! Cissy by Beelz3bub July 14, 2021 0 0 Get merch Get the Cissy mug. Buy Now — $32.95 See more merch