The term "lean mass hyper-responder" was coined by software engineer David Feldman on July 3, 2017 while posting in his low-carb diet blog: "Cholesterol Code." The blog post called "Are you a Lean Mass Hyper-responder?" quickly circulated through the low-carb community.
As background, the original term "hyper-responder" was already used by dietary professionals for years prior to Feldman's blog post. And in dietary literature, a "hyper-responder" is someone who adopts a low-carb diet, then experiences dramatic cholesterol elevation. So when Feldman wrote his 2017 blog article, he co-opted "hyper-responder," and crafted his new term "lean mass hyper-responder" to describe what he believes is a metabolically unique sub-set of all hyper-responders. Specifically, some hyper-responders begin a low-carb diet while already in possession of a very lean body mass. And yet in spite of this, they still --quite counter-intuitively-- respond with extreme cholesterol elevation. Additionally, these subjects experience a marked decrease in triglycerides, while exhibiting excellent metabolic health. The entire phenomenon defied a long-standing metabolic theory called "The Lipid Energy Model," presenting a scientific conundrum for Feldman.
Feldman believed that all this was a significant observation worth exploring. And his efforts eventually led to a 2023 research project called "The Lean Mass Hyper-Responder Study" led by Dr. Matthew Budoff and Dr. Nicholas Norwitz at Lundquist, UCLA.
As background, the original term "hyper-responder" was already used by dietary professionals for years prior to Feldman's blog post. And in dietary literature, a "hyper-responder" is someone who adopts a low-carb diet, then experiences dramatic cholesterol elevation. So when Feldman wrote his 2017 blog article, he co-opted "hyper-responder," and crafted his new term "lean mass hyper-responder" to describe what he believes is a metabolically unique sub-set of all hyper-responders. Specifically, some hyper-responders begin a low-carb diet while already in possession of a very lean body mass. And yet in spite of this, they still --quite counter-intuitively-- respond with extreme cholesterol elevation. Additionally, these subjects experience a marked decrease in triglycerides, while exhibiting excellent metabolic health. The entire phenomenon defied a long-standing metabolic theory called "The Lipid Energy Model," presenting a scientific conundrum for Feldman.
Feldman believed that all this was a significant observation worth exploring. And his efforts eventually led to a 2023 research project called "The Lean Mass Hyper-Responder Study" led by Dr. Matthew Budoff and Dr. Nicholas Norwitz at Lundquist, UCLA.
IN A SENTENCE: "Steve has always been a tall, skinny, beanpole of a guy. And then when he went on the carnivore diet, he was still skinny, but his cholesterol went through the roof. His doc said that overall he's pretty healthy, so he might just be a lean mass hyper-responder."
by Innocent Byproduct December 13, 2023
Get the Lean Mass Hyper-Respondermug. a scene or event with an excessive amount of combat with childish or simplified mechanics with clustered combatants in close to mediumly close proximity to other non friendly combatants
halbert - "wow this 1529 oil painting depicting The Battle of Alexander at Issus has a real hyper conflict going on huh james"
James - "this is why your girlfriend left you"
James - "this is why your girlfriend left you"
by the F.D.A November 21, 2024
Get the Hyper conflictmug. A fancy term for constantly having your head up your ass.
Used to describe certain groups of people who dial 911 for no reason with a BS medical complaint.
Used to describe certain groups of people who dial 911 for no reason with a BS medical complaint.
Patient: "Hello,911? Yes I think I'm having a stroke, I think I've had it for a month!"
EMT: "No sir, you have Hyper-rectalcranialitus. It's a pretty severe condition that you may need to get looked at. For removal of the cranium from rectum, it may require surgery."
YO HEADS UP YO ASS.
EMT: "No sir, you have Hyper-rectalcranialitus. It's a pretty severe condition that you may need to get looked at. For removal of the cranium from rectum, it may require surgery."
YO HEADS UP YO ASS.
by Cletus Filibuster September 6, 2016
Get the Hyper-rectalcranialitusmug. by GOB5855 June 15, 2016
Get the Hyper farmingmug. A group of people even smaller than a minority, not being recognized as part of LGBT, or ethnic groups. People like "trans racial", "MAP","dreamgender/dreamsexual"are all hyper-minorities. Unlike minorities, hyper-minorities are subject to being ridiculed because they are cringe and irritating to be around. So they are often made fun of online.
by Combat shorts August 28, 2021
Get the Hyper-minoritymug. by spegt December 24, 2022
Get the Hyper Diarrheamug. A collective group of mega-superclusters, (which are close together and make up a small part of the multi-supercluster).
'The other cosmic structure that's even larger than a supercluster is a hyper-supercluster, (ie. hypercluster): A collective group of neighbouring mega-superclusters, which only make up a small fraction of the entire multi-supercluster and it's also like the hyperverse.'
(Please read my definition of the hyperverse, multi-supercluster and mega-supercluster).
(Please read my definition of the hyperverse, multi-supercluster and mega-supercluster).
by DianaLuciusDeCollis July 12, 2022
Get the Hyper-superclustermug.