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Austin Speedball

When you take a Benadryl due to Austin, Texas's incredibly high amount of cedar and oak pollen in the air. But then you have to take a shot of espresso to counteract the inevitable drowsiness. Benadryl is a downer. Caffeine is an upper. That's why it's an Austin speedball.
Dude, I was sneezing all day and my eyes were super bloodshot until I took an Austin speedball.
by bp_austin March 30, 2019
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Tallahassee Speedball

Putting starburst and Skittles in a bottles of Mt. Dew, and when the Dew is drank, one is left with a congealed ball of starburst, Skittles, and Mt. Dew.
Before gym, he shotgunned a Tallahassee Speedball, and had a stroke on the track.
by Jakestastyballs January 6, 2020
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Cholo Speedball

The act of putting any mexican beer of choice into a bong, taking a fat rip, drinking the beer that’s in the bong, and finally blowing the smoke out.
Alan: Do you know what a Belushi is?

Peter: Shit the fuck up, dog. I’m crying to catch a cross fade.

Alan: With a Cholo Speedball? Okay, carry on good sir.
by mildpain March 16, 2020
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trump speedball

A cocktail of bleach mixed with a disinfectant
I tried the "trump Speedball" it left me feeling dirty
by Secrect Destroyer May 4, 2020
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Super Speedball

A mixture or combination of Cocaine, Heroin, and Fentanyl. A potentially deadly combination of illegal substances taken generally to achieve a mental, emotional, & physical euphoric “high”.
If one so desires to dance in the devil’s pyre 😈 🔥 playing a game of Russian Roulette, a “Super SpeedBall” will be your guide… ☠️ ~ Chief X
by Chief X September 25, 2021
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REO Speedwagon

When you're comfortable but suddenly need to take a poop and finally do after several minutes of contemplation because you can't fight that feeling anymore. Named because of the band's hit song "Can't Fight This Feeling"
"I was watching TV but a mud missile was kissing my underwear and I finally took an REO Speedwagon"
by CatDad1622 May 13, 2024
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Fragadelphia Speedball

A healthy drag of any THC cartridge paired with a delicious white Monster
Brandon was playing ranked with the boys and needed to hone his game after throwing, pulled out the Fragadelphia Speedball and clutched up for the win.
by littlestGill March 15, 2026
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