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A slang term/phrase meaning “what (are) you on?”
which is used when a person did/said something dumb or something you don’t agree with
Person A: Math is red!
Person B: wyo bro math is definitely blue!
wyo by papilord September 21, 2023
Related Words

Wyo Tech 

Automotive Lies and Deception. With Plenty of Nothing to do you'll find yourself in the baron waste land of Laramie craphole Wyoming with nothing but your dork in your hands.
Have fun with the Wyo Tech Furniture.
With my certificate of unknown excellence from Wyo Tech I have literally done nothing automotive with my career, I now build websites and pay off student loans from the worst 12 months of my life.
Wyo Tech by Charles Thomas April 8, 2007
what you on blood
"wyo 5"
me:shit, wyo
wyo 5 by anonymous December 7, 2021

Wyo Later? 

If you get asked this you're most likely bout to get laid.
Person 1: "Wyo later?"
Person 2: sayless we fucking @ my house.
Wyo Later? by CarterChenMN November 13, 2019

Wyo pigeon shit

This particular event occurs when a male cums in a women’s hair then proceeds to rub it in as conditioner.
Wow my hair is dry Darrick you should give me a wyo pigeon shit so I can make it silky smooth.
Wyo pigeon shit by Bigballz March 12, 2021
Wyoming is supposedly a state. Wyoming does not in fact exist, it is a distortion of space-time that only appears to exist. Anyone you've met who thinks they have been to Wyoming, or believes they have lived in Wyoming have had fake memories implanted by the U.S. government. This is because they cannot explain it, and it would cause a mass panic if the public knew the truth. If you attempt to drive into Wyoming you will wake up in Canada, naked, and with no memories. (This is how Canada gets new citizens).
"Oh so you say you've come from Wyoming the state huh?"