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Hippopotamus 

Q: Is a hippopotamus a hippopotamus or just a really cool opotamus?

A: A really cool Opotamus!
Hippopotamus by Entr' Acte December 24, 2009

herpopotamus

A fat chick that gives you herpes.
Ryan: Yo tom did you get with that herpopotamus last night?

Tom: yea that fat chick gave me herpes
herpopotamus by Killerkyle412 October 15, 2013

hippopotamus doorknob 

Noun. A process in which a person shoves an umbrella in his or her anus, and then promptly opens it up, thus making his or her asshole larger. The misguided soul then proceeds to put watermelon-sized anal beads into his or her rectum. This being must then try to regurgitate these objects into a friend's mouth. Finally, the friend runs to the nearest zoo naked and gets impaled by a rhinoceros.
- Damn son, why you so stressed today? Did ya take a hippopotamus doorknob recently?
- Yes, my anus is still sore.
- I'm sorry for your loss.

Hottopotamus 

A chick with a hot Or sexy face and a ugly or fat body. Similar to a body bag, opposite of a paper bag or a butterface.
I saw a sexy clerk at a gas station, but when she stepped out from behind the counter I realized she was a hottopotamus.
Hottopotamus by Phyregod August 13, 2009

HOOPTOPOTAMUS 

The Hooptopotamus (Hooptopotamus amphibius ganious) from the ancient Greek for "gay river horse" (Ιπποπόταμος), is a large, homosexual herbivorous mammal in sub-Saharan Africa that can fly. The hooptopotamus is one of the rarest creatures on earth and is the only flying mammal in existence. The Hooptopotamus is distinguished from his cousin, the Hippopotamus, by a set of fairy-like wings and his aptitude for species of the same sex, which has lead to his diminished populations.
Don't be such a frikin Hooptopotamus!
HOOPTOPOTAMUS by Hooptiehead July 6, 2010

hippopotamus plunger 

the act of taking a shit on your hand then making a fist and shoving it inside a guys/girls ass and thrusting it back and fourth
I totally just did the "hippopotamus plunger" and she loved it