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The word of "Doh", or more importantly sound of "Doh", is used in (but is not limited to) two meanings:

1. In substitution for a phrase implying something along the lines of: "He/She/They would...'''

2. A response to a thing, or situation, that is extremely lacking in intelligence.
(See Examples For Further Details)

*Contrary to popular belief, the pronunciation of "Doh" is actually more along the lines of "Cho" and most commonly assisted by a dip of the chin/drop of the shoulders.*
Ex 1:
Guy 1: "Dude, Terry just tried to tell me that, because of a chip he bought online, his stock Dodge Neon, now has 500 horsepower and is faster than/equivalent to the speed of light."

Guy 2: "Doh..."

Ex 2:
Guy 1: "I strongly believe that if I worked out for a good... 30 days non-stop, I could lift more than Ronnie Coleman in his prime."

Guy 2: "Doh..."
Doh by TheSledge973 November 17, 2009
Related Words
Doh dohc Dohoon DOHA Dohyun doh-doh dohicky dohm dohnut Dohyeong
expressing frustration at the realization that things have gone badly or not as planned
you buy a chick a drink and she doesn't put out
Doh by puddin tame June 12, 2005
Acronym for "Delayed Onset of a Hangover"
Tom drank from 4pm to 6am. He then attended class the next morning. Around 2pm that day, Tom began feeling sick to his stomach. What he was experience was DOH.
DOH by dgizzy April 12, 2007
use of kind word instead of bad word
instead of:crap
shit
damn
fuck
Doh by freaky deeky dutch March 5, 2003
The boss on the last level of the video game Arkanoid.
Doh Doh Doh Doh Doh Doh Doh Doh DOh Doh
Doh by LudwigVan April 7, 2004