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Well, shit in my mouth and call me your sister 

An sarcastic exclamation that can be used in a variety of ways. Usually used to to emphasize how glaringly obvious something that has been said is.
A: I had to go to school yesterday.
B: Well, shit in my mouth and call me your sister - student's going to school? Really?
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your sister 

The person all your guy friends want to fuck when they realize she isn't just yur little sister any more- she's your little virgin sister who is hot now that she has boobs and shaves her legs.
"Damn! Your sister is hot! When did that happen!?!?"
"Dude as your best friend, would it be weird if I fucked your sister?"
your sister by Sexy Stephy June 6, 2004

Your Sister is a Mister 

The ultimate comeback that were Steven Hawking’s final blessings to us before his passing.
Steven: Your sister is a mister... *final breath*

Man: What an OG that man was

stove piped your sister 

To have meaningful sex with ones sister.
i.e. Hey ziggy, I stove piped your sister last night and she loved it.

Your sister was right 

You’re a wanker, complete wanker. A fucking waste of time :/

(One of Wilbur Soot’s songs, found in the album “Your City Gave Me Asthma”)

your sister a mister

your sister a mister is possibly the worst insult ever created. It will destroy an entire dimension whenever it is used. Another language had to be made to create this phrase, and this is the rough translation. Calling someone's sibling trans is easily worse than Your mom gay, Your dad lesbian, Your granny tranny and Ur grandpap a trap are hardly insults copared to your sister a mister.
God: Are you a little bitch?
Me: Your sister a mister
God: *Fucking dies on the spot

your sister a mister

fred:your mom gay
joe: rour dad lesbian
steve: your granny tranny
brandon trembling from all the bad insults: your sister a mister
fred, joe and steve all explode