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di-nastiest 

Something or someone that is so nasty that the nasty has to be double to two nasties.
Man... you are DI-nastiest, but you're better than that man over there, he be tetra-nastiest
di-nastiest by BIG FABE! July 30, 2004
Used often by Marines, as a noun, in reference to individuals that do not meet Marine Corp standards. Generally in reference to physical fitness or appearance.
"'If any of you nasties set off one of these in the dark . . ." Keeping Faith, John Schaeffer and Frank Schaeffer, Carroll and Graf distributed by publishers group west.

"...that is of course if you nasties have what it takes to become part of my beloved Marine Corps. Get some!" mavericmarine, http://www.leatherneck.com/forums/showthread.php?t=33597&page=3

"If you hated the Marine Corps until you got your $30 grand, then all of a sudden you were a motivator, you will eventually fade back into the realm of nasties." warrior0369, http://www.militarytimes.com/forums/showthread.php?t=1559730

nasties by wongerrrrrr November 3, 2008
When somebody is out of cigarettes and they rip up a bunch of cigarette butts and re-roll them into a whole cigarette.
"Hey do you have a smoke?"
"No dude, I haven't had any all day and I've been needing one so I even rolled a nasties."
Nasties by McStallion September 30, 2011
Bacterias or germs, mainly used by fags.
We gotta keep the nasties outta my body by sneezing those mofos out.
Nasties by Toxic Rage November 19, 2004

shack nasties 

Noun: Stuck inside for too long. An urge to get out and enjoy company and outdoor activities. Usually felt after a long winter or a government overreach from a corona scare. Also known as Cabin fever.
"Hey Chels, I'm getting the shack nasties, this governor wont let me leave the house. Ima sneak over for a rona handy."
shack nasties by Badge1 May 13, 2020

big nasties 

Beach ball sized droopy titties
Pat: "Why does yo sister keep trippin?'"
Dirty D: "Because she has big nasties. You want to sqeeuze 'em?"
Pat: "Roll those bitches up"
big nasties by PBZ November 18, 2007