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Bad-Aim Syndrome 

In a first-person shooter video game's online multiplayer (ex. Call of Duty: Black Ops), it is when no matter what the online player does or what gun he or she changes to, the player can never seem to get their aim on the enemy. This usually results in the player shooting all around the foe and and never hitting them thus resulting in the them being shot and killed by such enemy(s) over and over; very frustrating. Symptoms can last anywhere from a hour to a week and in the worst cases longer. Cause is still unknown. Cure is still also unknown but usually some good fast food or some vaginal sex helps relieve the condition; oral sex has also been documented to help.
Gamer 1: "Dude its no use, I think I have bad-aim syndrome to the max. I can't shoot anyone."

Gamer 2: "Damn, change something up quickly or hey even better take my girl for the night and clear that up and get better."
Bad-Aim Syndrome by TERRORMOTO December 26, 2010
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Family Guy Personality Syndrome (FGPS) 

When someone is overly obsessed with the hillarious hit tv-show Family Guy. Some common symptoms of this can be things like; boring the living crap out of your friends by telling the same Family Guy jokes over and over, turning all of your conversations into "did you see yesterdays episode?" or "so Peter was like...". One of the most irritating and shit indulcing symptoms is retelling an entire episode word by word thus extremely boring the other person. If not treated it can leave your personality consisting of nothing but Family Guy jokes.
Family Guy Personality Syndrome (FGPS) victim: Did you see yesterday's episode?!? I almost shit my pants twice!!

Diego: Ehh, no.

FGPS victim: Welllll, let me tell you the whole episode detail by detail! Don't worry it will only take about half an hour and be nowhere near as funny as actually watching it.

*Diego has now left the conversation, or risk getting a severe ear injury.*

Lone Paps Syndrome 

When a person believes he is cool and surrounded by uncool cats. He prefers to hang around in his house talking about imaginary adventures that cool people would have. He cannot bear to hang out with real people and realize that he is uncool so he spends his days in solitary confinement. Normally they do not have any friends because they never seem to find someone as cool as them.
Andres: Alan let's go to the club with your friends

Alan: No, I hate going to the club with all my lame friends to meet ugly girls, I'm way better than everyone else. I would rather hang out with myself talking about how cool i am

Andres: you have lone paps syndrome, ill go hangout with real people instead

1 o'clock syndrome 

1 o'clock syndrome is when a person stays up on their laptop later than one o'clock just looking at funny pictures and having random discussions on Facebook. As the subject's condition progresses headaches, upset stomachs and even paranoia may occur. In the final stages of 1 o'clock syndrome the subject will become extremely bored, too tired to do much yet not tired enough to go to sleep and will resort to watching My little Pony friendship is magic for two or more hours however the subject will reject being a brony.
"You sleep well last night?"
"Nah I had mega 1 o'clock syndrome."
"How so?"
"I thought demons accompanied by Dracula were stalking me and I ended up watching seven episodes of my little pony to pass the time."
"Lol I didn't know you were a brony."
"F*ck you I ain't no brony."

empty catbox syndrome 

Combination of "empty nest syndrome" and "catbox," describing the empty feeling when, for whatever reason, you no longer have a cat (and the accompanying turds in the catbox) to take care of.
Fluffy left for college. I'm suffering from empty catbox syndrome.
empty catbox syndrome by Ae5Ea8 March 29, 2015

Sniveling Anus Syndrome 

A very uncommon syndrome acquired from constant and rigorous wiping of the asshole. Most common symptoms include (but are not limited to): bleeding from the anus, discomfort when sitting down, a little voice coming from your rear end telling you to eat more Chipotle, and uncontrollable desire to dress and act like Joseph Gordon-Levitt did in 500 Days of Summer.
Me: I just can't stop bleeding from my asshole doc.

Doc: Have you been watching 500 Days of Summer?

Me:...What if I have?

Doc: I'm afraid that you have Sniveling Anus Syndrome.

Bowel Nigga Syndrome 

To have Bowel Nigga Syndrome, you must be born into a nigga household with birth defects.
“Look at this nigga ovah here. He must have Bowel Nigga Syndrome with his ugly ass.”