"That guy" refers to the narcissist inside each and every man. "He" is "That guy" when he gives into the urges (usually pertaining to sexual gratification) to the detriment of those around him. Nobody wants to be "That guy".
Bob: "Dude... don't freak... I got a blowjob from your sister last night ... but I don't want to be 'That guy'".
Another Bob: "Look at 'That guy' next to 'prince cassius' in the fashion section of the evening standard".
Another Bob: "Look at 'That guy' next to 'prince cassius' in the fashion section of the evening standard".
by jeffreythefarmer2 August 17, 2010

by VVonmywaist May 27, 2011

by sindhimanhroo June 8, 2009

by why are the all taken1589 April 11, 2019

by 1_cinnamon_1 December 8, 2014

A blended word of girls and boys. G for girls and Y for boys, the U just brings it together. Used as not to offend any one.
As Joe walked into the meeting he said in a voice so all the attendees, both the women and men, could hear him say " Howdy guys, how is everyone doing today? Are you guys ready to get the meeting started?" Everyone, male and female, was ready to start the meeting.
by Vanilla Gitty Up July 29, 2020

Term of brotherly advice, often given to oneself, to avoid acting like embarrassing dickwad as seen on YouTube or other social media.
“Did you see where Katherine Heigl’s husband got a tat with her zodiac sign and birthday?"
“Don’t be that guy.”
“Did you see where Rick Perry couldn’t count to three on the presidential debates?”
“Don’t be that guy.”
“Don’t be that guy.”
“Did you see where Rick Perry couldn’t count to three on the presidential debates?”
“Don’t be that guy.”
by Otisregrets November 24, 2011
