A meme in which a engineer from the game Team Fortress 2 says the line in a comfirming tone to a question. It is a common answer to yes-or-no questions.
by SpiritmanderTheCharmander August 06, 2022

The universal response around the world when a person has spent their money, time and or energy on some straight up bullshit. Not handlin
You: (super excited) hey guess what I got for our girls weekend?
Me:( grinning ear to ear) what bitch??
You: a whole zip of trees and I only paid 25 bucks for it,
Me: lemme see.
( After looking, smelling, and smoking it along with vomiting myself into an asthma attack.)
Me: bitch you almost killed me with that nope ass shit. Wtf, you got played.
Me:( grinning ear to ear) what bitch??
You: a whole zip of trees and I only paid 25 bucks for it,
Me: lemme see.
( After looking, smelling, and smoking it along with vomiting myself into an asthma attack.)
Me: bitch you almost killed me with that nope ass shit. Wtf, you got played.
by QueenyOmygodess July 09, 2024

by spongeboblover101 April 20, 2018

He's outlived his usefulness.
by Hym Iam July 16, 2025

No, nah
by cannon chris March 31, 2009

by felixh November 14, 2016

Stands for "net option pricing effect". NOPE is a stock trading theoretical model that estimates the performance of a stock's price using historical pricing data and deep learning. It is a popular tool used for earnings season as it is very accurate in picking the wrong direction of a stock's price movement after the company releases their earnings report.
Girl: "INTC NOPE pre-earnings estimate: Right now preliminary bullish (+3.45 sigma) but let's see!"
Boy: "Time to NOPE this and load the boat with puts!"
Boy: "Time to NOPE this and load the boat with puts!"
by buttercoconutbiscuit October 27, 2020
