People with Trans Derangement Syndrome have been trained to have an extreme adverse Pavlovian response to anything suggesting 'trans'.
The mere utterance of the word trans or they/them bypasses the higher-thinking circuitry of the brain and triggers the primitive rage centres to go off.
The mere utterance of the word trans or they/them bypasses the higher-thinking circuitry of the brain and triggers the primitive rage centres to go off.
Person 1: “is JK Rowling ok? They seem mentally unwell”
Person 2: “no, seems like they have a serious case of trans derangement syndrome (TDS)”
Person 2: “no, seems like they have a serious case of trans derangement syndrome (TDS)”
by Robert_G_ September 4, 2025

This is the actual comprehensive definition of TDS / Trump Derangement Syndrome.
(All the other definitions appear to be people just throwing mud at each other.)
TDS is a blend of psychological phenomena related to bias, prejudice, and cognitive distortion. It was coined Trump Derangement Syndrome due to the extreme hatred of Donald Trump by the managerial class/establishment and the NPCs and/or low information voters that follow their command.
TL:DR
In simple terms, this phenomenon occurs when someone is so biased that they interpret everything from a person or thing they dislike in the most negative way possible. For instance, if you wave hello and say good morning, they might think your friendly gestures are actually hidden insults or ominous threats. It's a form of "persecutory paranoia" and/or "hostile attribution bias".
Projection issues for those suffering from TDS:
People with TDS often see any neutral or positive stance as covert support for the person they hate, assuming that those who don't share their negative view are hidden supporters. This reinforces their paranoia and resistance to differing viewpoints.
These factors create a syndrome where hatred or bias blinds people to objective information and critical thinking, leading them to embrace propaganda, avoid independent analysis, and cling to their negative views.
(All the other definitions appear to be people just throwing mud at each other.)
TDS is a blend of psychological phenomena related to bias, prejudice, and cognitive distortion. It was coined Trump Derangement Syndrome due to the extreme hatred of Donald Trump by the managerial class/establishment and the NPCs and/or low information voters that follow their command.
TL:DR
In simple terms, this phenomenon occurs when someone is so biased that they interpret everything from a person or thing they dislike in the most negative way possible. For instance, if you wave hello and say good morning, they might think your friendly gestures are actually hidden insults or ominous threats. It's a form of "persecutory paranoia" and/or "hostile attribution bias".
Projection issues for those suffering from TDS:
People with TDS often see any neutral or positive stance as covert support for the person they hate, assuming that those who don't share their negative view are hidden supporters. This reinforces their paranoia and resistance to differing viewpoints.
These factors create a syndrome where hatred or bias blinds people to objective information and critical thinking, leading them to embrace propaganda, avoid independent analysis, and cling to their negative views.
Examples of TDS, Trump Derangement Syndrome:
Simple Example: Sarah, who dislikes John, interprets his friendly “Good morning” and smile as a disguised insult. She believes he’s mocking her, even though his intentions are completely harmless.
Real Life Example: Destiny (YouTube) is a prime example of someone exhibiting extreme TDS (Trump Derangement Syndrome). (Also see: The Rationalization Hamster)
Simple Example: Sarah, who dislikes John, interprets his friendly “Good morning” and smile as a disguised insult. She believes he’s mocking her, even though his intentions are completely harmless.
Real Life Example: Destiny (YouTube) is a prime example of someone exhibiting extreme TDS (Trump Derangement Syndrome). (Also see: The Rationalization Hamster)
by ApplesPotatoGardner August 20, 2024

Deranged Grindr Syndrome (also known as DGS) is a psychiatric condition affecting an unknown number of gay men who use Grindr for sexual purposes. People with DGS may exhibit a wide variety of symptoms including, but not limited to:
- Ghost-facing: Attempting to engage in chat with other users without sharing any pics of themselves
- Hole-bombing: Sending unsolicited images of their gaping holes to complete strangers
- Pic-collecting: Requesting images from other people when they haven’t shared any pics of themselves
- Wounded ego: Impaired ability to cope with rejection, such as demanding an explanation for why a complete stranger is not attracted to them
- Silent treatment: Engaging in extensive chat with another user and indicating an interest in meeting up for sex, and then going silent and never responding again
- Ghost-meeting (different from ghost-facing): making an actual plan with someone from the app to meet in person, exchanging location details and setting a specific time, and then ghosting the person with no warning or explanation while they are sitting there waiting for you
- Stalking: tracking another user’s online presence and bombarding them with messages each time they come online
This is not a complete list of possible symptoms included under the diagnosis of Deranged Grindr Syndrome (DGS). People with DGS may exhibit mild or severe symptoms. If you or someone you love suffers from DGS, help is available. Speak to a mental health professional.
- Ghost-facing: Attempting to engage in chat with other users without sharing any pics of themselves
- Hole-bombing: Sending unsolicited images of their gaping holes to complete strangers
- Pic-collecting: Requesting images from other people when they haven’t shared any pics of themselves
- Wounded ego: Impaired ability to cope with rejection, such as demanding an explanation for why a complete stranger is not attracted to them
- Silent treatment: Engaging in extensive chat with another user and indicating an interest in meeting up for sex, and then going silent and never responding again
- Ghost-meeting (different from ghost-facing): making an actual plan with someone from the app to meet in person, exchanging location details and setting a specific time, and then ghosting the person with no warning or explanation while they are sitting there waiting for you
- Stalking: tracking another user’s online presence and bombarding them with messages each time they come online
This is not a complete list of possible symptoms included under the diagnosis of Deranged Grindr Syndrome (DGS). People with DGS may exhibit mild or severe symptoms. If you or someone you love suffers from DGS, help is available. Speak to a mental health professional.
Deranged Grindr Syndrome (DGS) is like when this guy with no pics wrote to me demanding that I share my private photo album with him, and then he bombed me with 15 pics of his gaping hole, and he got mad and called me rude when I didn't respond. Major DGS.
by xxxtraspecial June 2, 2024

an individual’s unhealthy obsession with Joe Biden. Often displayed by MAGA cult members and leadership.
by Evildeadchud May 23, 2025

Canadians and Europeans are the most likely to have it. It's a sickness in which individuals live such uninteresting lives that their only source of enjoyment is hating on the world's greatest nation. The most common symptoms include flexing irrelevant geographic information that no one cares about, flexing free healthcare that comes with a tax rate four times that of the average American, and flexing colonial wealth from Africans' backs (Françafrique).
European: whats the capital, coat of arms, head of state and date of formation of Montenegro?
American: Who tf cares?
European: Bro you stupid American schools suck, smh
American: You got American Derangement Syndrome
American: Who tf cares?
European: Bro you stupid American schools suck, smh
American: You got American Derangement Syndrome
by aussiewhowantstobeamerican August 8, 2021

1) a gaslighting term used to convince others that being concerned with, actively against and/or spreading awareness of President Trump's dismantling of the United States' democracy and humanitarian freedoms is a sickness.
2) a gaslighting term used as an attempt to make someone who resists President Trump dismantling of the United States democracy and humanitarian freedoms feel in the wrong.
2) a gaslighting term used as an attempt to make someone who resists President Trump dismantling of the United States democracy and humanitarian freedoms feel in the wrong.
All you do is talk about and post about what Trump is doing. You must have Trump Derangement Syndrome.
by American citizen May 22, 2025

Hitler derangement syndrome is a pejorative term, usually for criticism or negative reactions to Adolph Hitler that are perceived to be irrational and to have little regard towards Hitler's actual policy positions, or actions undertaken by his administration. This term is usually used by Nazi sympathizers when defending their admiration for Adolf Hitler.
The liberals were placed in camps for the mentally ill because they suffered from Hitler Derangement Syndrome.
by HistoricalData February 9, 2025
