Quite literally the summation of the words “big” and “oof”. In other words, a quicker way of saying “big oof.” All drug-related references to the word are irrelevant in this context.
“Big” + “oof” = “boof”
“Big” + “oof” = “boof”
Person 1 - “I accidentally uploaded my porn folder to the homework Dropbox. FML.”
Person 2 - “Damn, that’s a boof.”
Person 2 - “Damn, that’s a boof.”
by CFidel February 12, 2019
Get the Boofmug. (Secondary definition) The action of barking done by a large dog (known as a boofer), colloquially represented as an onomatopoeia reflecting the deeper pitches and depth of tone of a larger dog. It is the deepest level of the Boof-Borf-Bork-YipYap scale of dog barking.
by TheloniousBird October 7, 2018
Get the Boofingmug. During a discord server a Youtuber FuriousFade made up a word "boofed" his definition is a "hood term in the streets." Also use Code "FuriousFade"
by Gxrzi February 16, 2019
Get the Boofedmug. 
To make a careless mistake, usually by an inferior competitor
Can be in sports, but also in speeches or performances
Trying so hard go do something right, but yet doing everything wrong
Can be in sports, but also in speeches or performances
Trying so hard go do something right, but yet doing everything wrong
1) Joey had an open net for the game winner, but he totally boofed it... Joey sucks!!!
2) Wow, Claudia totally boofed her presentation. I thought she would have gotten better after last time... “nah I think she’s just a loser”
2) Wow, Claudia totally boofed her presentation. I thought she would have gotten better after last time... “nah I think she’s just a loser”
by righteousrandy63 June 18, 2020
Get the Boofmug. A fat blunt (a fat doink)
by Jmoney5811 October 16, 2018
Get the Boofmug. Hey kid! You want some boof?
by Wilbur's hoe July 1, 2021
Get the Boofmug.