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defriend 

(v) To remove someone from your livejournal friends list.
"I defriend people who post quiz results. Get a life!"
defriend by Coell May 14, 2005

Defriend 

The act of deleting someone on an online socializing site like Facebook or Myspace.

This usually happens when someone you don't know requests to be your friend so you accept them to see their profile. Once you realize that you don't know them or that they are a complete creeper, you attempt to 'defriend' them. This usually proves to be a nuisance and a pain to figure out how to do.
Person 1: I'm going on this trip to France and a guy from another school friended me, I messaged him 'cause I wasn't sure who he was, and he gave me a total creeper response.

Person 2: Man, defriend that fool.
Defriend by B-RizzleforShizzle March 4, 2009

Defriend 

To remove a friend from your Facebook or Myspace because you misfriended them (accidentally "friended" them or added them as a friend).
I had to defriend this dude I thought I knew from my high school days, but it turned out I didn't. He was sending me all sorts of events spam!
Defriend by Sartorialist February 25, 2009

defriend 

to stop being friends with someone on Facebook and removing them from your friendship list.
I defriended all my kooky friends on Facebook.
defriend by Bert LaVey February 26, 2018

Defriend 

When you have a friend that is no longer use full to you
Friend1:give me money
Friend2:no
Friend1:fine I’m defriending you bitch
Defriend by Gavin McDivitt April 29, 2020

Defriend 

The opposite of Befriend, esp. on social media. To walk away from a friendship using specific criteria.
I am averaging 25+ a day I am defriending.

Was almost to 5K on 3-21-2020

Today 3,965

I am taking a risk having you defriend me using my specific criteria...lol
Defriend by towilmusic June 24, 2020