Tweek 

To be high and see something that is not not present.

I was driving around I started tweeking , I thought I seen someone on the road

Tweek by URBAN HOODS January 19, 2015

tweek 

to adjust or fix

Let me just tweek your computer.

tweek by Tracy Lukeman October 20, 2003

Tweek 

Gay. Twitchy. Spaz. Loves Craig, Kenny. An adorable bean. GAH!

“Oh my god, Tweek and Craig are holding hands” gasped a random person on the street

Tweek by ThatSouthParkYaoi July 1, 2018

Tweek 

A character from the T.V show "South Park". He has very messy blonde hair and supposedly sufferes from A.D.D but his twitching and nervous personality is due to the large amounts of caffeine he consumes. In Series 6, Tweek became the main characters replacement for Kenny, alongside Butters, after he "permeanantly" died at the end of the previous series.

"Tweek's the worst character ever."
"Yeah. Worse than Towelie."

Tweek by Issy Aidsfunop January 22, 2006

tweek 

to be overly excited at a situation or event that is highly positive and causes exuberance beyond classification of excitement.

Scott won a vacation to Hawaii, a place he always wanted to go, causing him to call his friends and tweek.

tweek by BT14 August 3, 2007

Tweek 

To pinch or flick...

"I tweeked her nipple and she tweeked my clit with her tongue."

Tweek by Junebug December 28, 2005

Tweek 

A smol chubby talented gay babey.
Appears on southpark. He's addicted to coffee and meth, and loves to play the piano. He's a good singer.
He and Craig Tucker are a couple. Like I said earlier, he gae.

TweekXCraig is my favorite episode!they were so gay in it! Especially Tweek!

Tweek by The_emo_bunny_ August 9, 2019