Often used to imply a lesser class of person, with no style or class. Usually of poor taste and probably never checks themself in the mirror before presenting themselves to the public. Can also be used as an affectionate term between friends to convey messages of admiration and love, usually a retaliation to an jovious insult.
"Piss off! You're a total skank!"
"What time you want to head out, you big skanky ho."
A person(commonly a female) that has had sex with many people. But wishes to stop her abusive past by givving money to homeless children in Africa, Donating to charties, Volunteer work, or Any form of Social work.
Pamela was a Skank, but then she devloped a STI and now she does many Socialworks for people.