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Random Pavarotti Syndrome 

Noun: A condition in which the afflicted individual bursts in to raucous operatic verse at highly inappropriate times.
He has Random Pavarotti Syndrome; always doing The Merchant of Venice in the library...
Random Pavarotti Syndrome by Fu Fu October 30, 2007

The Harry Syndrome 

This is when an IT Desktop Engineer has a mental breakdown with chronic and unresolved grief caused by an over-demanding customer with an accent.
"oh maaaaaaan I think I got The Harry Syndrome cause i am so tired of creating a batch file that would sort a customer's David Hassellhoff CD and DVD collection"
The Harry Syndrome by Geek_Chic February 13, 2008

Alien Hand Syndrome 

To be unable to control ones arm or arms. This can also be present when regarding the entire body (see Alien Body Syndrome).
Ross: Dashton, why did you nock over that expensive drum kit?

Dashton: Sorry, alien hand syndrome.

Niagara Falls Syndrome 

When a girl does something or sees something that makes her vagina get extremely wet
Chris: Madi, why do you look like you peed your pants?

Madi: Well you walked into the room and I got Niagara Falls Syndrome!

Chris: That happens all the time!
Niagara Falls Syndrome by Mizfku December 16, 2010

Man Jaw Syndrome 

or "MJS" for short.
Condition in which a female has an abnormally square/manly jaw.
Emily Deschanel (from the TV series, "Bones")

Jim: goddamn homie, she's fine!
Tim: yeah, but she's got a serious case of Man Jaw Syndrome
Jim: shitbiscuits, you're right
Tim: you bet you're black ass I'm right

High School Thot Syndrome 

When a female has gone completely rogue, and undergoes a process of thotism, completing the process and thus being given the diagnosis of being a thot- also known High School Thot Syndrome
“Did you hear about Jessica? She cheated on her boyfriend twice in the past week!” “The doctor said there’s only one explanation for it, she was diagnosed with High School Thot Syndrome.”