Any of a large amount of spells from the Magic: the Gathering card game that destroys a creature or removes it from the game, especially at the most frustrating time possible in a game.
I finally get a creature on the board, and the next thing I know, BOOM - kill spell!
When a woman has a fainting episode. Usually associated with stress or perceived drama. fainting passing out
Getting a flat tire, having no cell service, and being stuck in the 90 degree heat overwhelmed Sally's delicate constition causing her to have another drawin spell.