One word with so many facets, meanings, and applications. This is not an attempt to cover them all, but merely
one of them. Anyway, one facet of it can be used in the context of describing someone or possibly a group of people that gets severely taken
advantage of, or totally screwed in some way, shape, or fashion.
1.
The motherfucker that gets THAT used car is in for a big surprise....
2. Hear about that Tornado?....A whole lot of
motherfuckers don't have a place to stay...
3. Those victims of the Haiti earthquake, Those Poor
motherfuckers are in some deep dogshit now