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1. A brand of beer (or malt liquor) with an alcohol content of about 8%. Usually favoured by people with low incomes, because of the high alcohol content and cheapness.

2. A .45 single action revolver, made by Colt's Manufacturing Company.

3. An alternate name to the song "Crazy Rap" by Afroman.
No money? That's okay, we can drink Colt 45!

Remember to cock the hammer of that Colt .45

Colt 45, and two zig zags, baby that's all we need...
Colt 45 by Kieta October 14, 2007
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Glock 45 

A polymer framed, double action only semi automatic pistol chambered for the .45 Automatic Colt Pistol (ACP) cartridge. Manufactured by the Glock company of Austria. Comes standard with single column six round magazine.

Can be modded to a fully automatic machine pistol with a 26 round capacity (high cap mag).
A Glock 45 pistol at my local gun shop.
Glock 45 by Young Reezie January 29, 2008
Related Words
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A buttocks that is as wide as the span of the hands on a clock when it is 3:45. This phrase can be heard in the Beauty and the Beast skit on Saturday Night Live.
Bart: That girl I had a date with last night... Her butt was too small.

Fred: Well, what kind of butt are you looking for?

Bart: I don't know... I like a 3:45 ass.
3:45 ass by missnewboooootie November 22, 2009
An efficient means to getting rid of aggravtions.
Feeling kinda down? Down a Colt 45.

Cat pissing on your car tires? Draw your Colt 45.
colt 45 by Lars Sandman December 24, 2008

Colt 45 and 2 Zig Zags 

A song by Afroman.

Means a beer (Colt 45), and 2 joints (2 zig-zags).

Colt 45 was once a very popular beer, and zig-zags were the infamous brand of rolling papers for joints.
"Colt 45 and 2 zig zags, baby that's all we need".
Colt 45 and 2 Zig Zags by Jimmib December 11, 2007
a talented kpop tiktok editor 😩‼️ the best j-hope stan 😁
hey do you follow @10.13.45 on tiktok? their edits are so cool!
10.13.45 by anonymouspersoniglol December 23, 2020
its kind of like a liquored up beer that sneaks up on you all of a sudden
guy on plane: can you explain these
flight attendant: well colt 45 is like a liquored up beer that sneaks up on you all of a sudden

from soul plane
colt 45 by zach s. August 11, 2005