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Brian Tumor

"Brian Tumor" (noun): A highly contagious and profoundly debilitating condition primarily affecting pre-adolescent males named Brian, typically observed at age 12. The disease manifests as an uncontrollable expansion of ego and a dramatic increase in the frequency of unsolicited, poorly timed, and often cringe-worthy attempts at humor. Symptoms include a marked decline in tolerance for other people’s well-being, an overwhelming need to insert oneself into every conversation, and an alarming tendency to dominate social situations with an incessant stream of 'inappropriate' jokes.When you're stuck in a group chat with a 12-year-old named Brian, and he won't stop making terrible puns, interrupting every conversation, and somehow turning everything into his personal highlight reel. It's like his brain is a tumor, growing uncontrollably, with zero regard for anyone else's sanity
Bro, I can't take it anymore. Every time Brian speaks, it's like a Brian tumor of bad jokes and unsolicited opinions. Someone please save us.
by sawcon May 14, 2025
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Big Brian Ilel

A guy who plays valorant with yolor3stis and Tetoris and has taken the istanbul servers by storm with his big brain plays on the agent Omen.
Omg clip that, that was suck a Big Brian Ilel move
by Ilel kalliakmeme October 26, 2020
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Brian

A: I can't believe you did this.
Brian: *giggles*
by big fat juice November 22, 2021
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Brian

A nice young man. Smart, cute, and handsome. Great athlete, best at football. lovable, big dick, every girl dream guy
Brian my dream guy
by ——;/ June 6, 2024
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Brian Etzel

Josh Harrison thinks he smart but has he met Brian Etzel? Oh my wasn't he #2 in Mechanical Engineering at Penn State? Yes he was. He must be so smart
by Brain Pretzel September 17, 2020
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Brian

One of the best guys you'll ever meet. He's the biggest dork with the biggest heart, and no matter what kind of mood or funk you're in the always manages to lift you out of it just with his presence. Brian is easily the type of guy that you could see yourself spending the rest of your life with, he's loyal, sweet, hardworking, and kind beyond all measures. Brian is an irreplaceable individual who makes more of an impact on people's lives than he knows of. If you have a Brian in your life, give him the absolute world because he deserves that and more.
Brian is the best boyfriend ever
by dxhxnxe September 9, 2022
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