Rye's Syndrome

A severe illness of da brain caused by excessive consumption of northeastern-USA white lightnin'.

Huck Finn's father may indeed have been a southern boy, but he still exhibited Rye's Syndrome-like symptoms near da end of his life, such as hallucinating about snakes, vampires, zombies, and devils attacking him.

by QuacksO September 17, 2022

Alligator Syndrome

A syndrome that affects the liver caused from eating too much donkey meat.

Phil Lesh contracted alligator syndrome after eating too much donkey meat.

by Thomas the syndromeist September 17, 2022

irritable bottom syndrome

A syndrome when you drop so much bottom banter it hurts

Crostin: Yo PJ
PJ: Yo you got irritable bottom syndrome (IBS)?

by razvanovicio September 20, 2022

Weed Cat Syndrome

A phenomenon where a fictional character gets unbelievably popular the second it's revealed.

This phenomenon is named after the nickname given by the internet to the Pokemon Sprigatito, who got popular after Pokemon: Scarlet and Violet was announced.

Looks like another character on Twitter has Weed Cat Syndrome.

by Theesl September 20, 2022

down river syndrome

When a person has chromosomal damage from living down river near Detroit

Man that guy has a bad case of down river syndrome

by Kauai-kimo September 23, 2022

The good wife syndrome

When men watch this show it immediately shrinks their balls to the size of raisins.

Hey man have you seen Connor lately? No, why? He is tiny as hell and talks with a lisp. Wow he must have the good wife syndrome.

by Larrykernen September 23, 2022

Career Woman Syndrome

Noun. : What a woman gets when they have emotional baggage or haven’t had luck with relationships, so they just focus on hyper independence and their careers.

Damn shawty does nothing but talk about how she is independent or her job. I think she has career woman syndrome.

by FlackoRaikiri32 September 25, 2022