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Any large person who refuses to engage in daily personal hygiene, often smelling of rancid garbage and/or rotten cheeseburgers with onions on a hot day. Also the same person who refuses to courtesy flush who may have had a gastro sleeve whose stool is unbearable to the point of choking and/or vomiting.
Oh oh, get the spray out....here comes Big Nasty!
Big Nasty by Unc Vinny September 27, 2019
Related Words

Kash Nasty 

The best person in the world; you are literally good at everything you do.

Dear Kash Nasty, why are you so perfect
“Do you know Kash Nasty, she’s the most perfect person alive
Kash Nasty by The ONLY Kash Nasty January 25, 2021

Stove-Top Nasty 

The coolest of the cool. Like if The Fonz and a freezer had a child in Antarctica.

-But then, somewhere in Alaska, a young Brad Pitt smoking a cigarette had an immaculate conception caused by 'the holy spirit of swagger' whispering in his ear. And he bared that child.

-And then, those two babies grew up to be adults, and met each other, and then fucked. (in an igloo)

--and those two conceived a child, the female carried that child for 9 months, and then gave birth to a healthy baby, and then put sunglasses on that baby...
...that baby would be 'Stove-Top Nasty'
"You just got your dream job?!?! Stove-top nasty."

"That live Led Zeppelin concert last night, where they resurrected the dead members of the band just to play for 12 hours straight was fucking stove-top nasty."

"She IS stove-top nasty, marry her this instant!"

"What does stove-top nasty mean?"
"Its something some of us are just born knowing the meaning of, and others aren't."

"It's all stove-top nasty, nigga"

"If Jesus was a modern day gangsta, he would be fucking stove-top nasty, for sure."
Stove-Top Nasty by ~Easy E April 14, 2014

Duck Dynasty (Duck Dy-Nasty) 

When you ass is so tight and you fart, it sounds like a duck call.
Duck Dynasty (Duck Dy-Nasty) I am so stressed out, I had a full day of duck dynasty

match my nasty 

to have similar sexual desires as another
She won't let me go down on her, she don't match my nasty .
match my nasty by anonymous_tales February 12, 2017

Ya lil nasty 

Ya lil nasty is a phrase you say to someone when they are being shady or bitchy. If you say Ya lil nasty to a person they are either excluding you, talking shit about you or being an asshole.
friend 1: omg guys i have to tell u something!

friend 2: tell us!
you: omg what is it?!
friend 1: oh not u only (friend 2) sorry!
you: Ya lil nasty.
Ya lil nasty by cherrybombgirl June 10, 2018