That's What's Up

A way of agreeing to what the other is saying. Or if they ask you a question it can also mean that you are down to do what they're asking.
1:"Ay mayne, i got this killa, we blazinituptoday?"
2:"Shiiiit, that's what's up!"
by MonalisaelisaDelafusa April 09, 2009
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Whats up with the whats up?

Whats up with me and you. When are you gonna let me get some.
Boy: Ayo, Whats up with the whats up?
Girl: Fuck outta here, I got a man. No Single Ladies shit.
Boy: ....Fraud.
by Ctfu February 10, 2010
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what's up with that

A phrase used to ask about something odd, or what the point of something is. The word "that" can also be replaced with whatever noun the person is asking about. It is also common to inerject the word "fuck" into the phrase to express shock or discust.
What's up with the smirk?
Look at all those bags on the road. What's up with that?

Person1: What the fuck's up with your hand!?
Person2: Ahh! Why are you just standing there?! Take me to the fucking hospital!
by Cinymin86 November 16, 2009
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That's what's up

Meaning that you fully understand and/or agree and find yourself excited about the idea or suggestion proposed.
Friend 1: "Yeah so I'm thinking we chill before, and then hit the club by 9. Got mad beer at the crib anyway"
Friend 2: "That's what's up"
by KelsBels April 06, 2008
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what up

How is it goin?
by Anonymous March 24, 2003
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Whats Up?

What is happening wiht you, How are you, whats going on?
Something that LouAnn doesnt understand.

Usual response: Nothin Much
**Do not reply 'HI' or with another 'Whats Up'**

A common phrase that most people understand & use each day.
Carl: Hey Dude
Mark: Hey Whats up?
Carl: nothin much
Mark: Cool
by Ednabrowneye13 January 18, 2009
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