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SIS

Abbreviation for: "Sisters, In, Spirit". Your Best Friend or Bae. Usually used to refer to someone really close to you, someone you spend a lot of time with, like your sister.
Girl: OMG, squad on fleek!
Girl 2: yas, we look #Fabulous
Girl: Yas Sis Yas!
by ChocolateWafflez April 15, 2015
mugGet the SISmug.

SIS

a genderless term much like "bro" or "dude"

you don’t have to be BFFS. You don’t really even have to know them. If she seem chill. then SISSSSSS is what they should be called!
JACK: *texts Jill*

“ SIS! You’ll never believe what popped up on Greg’s phone!!”

Jill: “Girl, SPILL!”

Jack: “Some HOE’S NAME! Do you think he is cheating on me?!”

Jill: “ SIS! YES! Leave his ass!”

****you can also use it in less dramatic scenarios****
by URB@NL3GEND March 4, 2020
mugGet the SISmug.

SIS

Snickering in Silence
new for LOL because it applies much more than LOL when texting/typing and trying to be quite
While texting in class i received a message with a prime time to say "thats what she said" and/or "reminds me of my saturday night" or even "I get that all the time" so I sis'd vs lol'ing

"idk what happened it just went everywhere after i touched it"
sis
"reminds me of my saturday night"
by kevin "k-bone" December 25, 2009
mugGet the SISmug.

SIS

Smirk in Silence:
The act of putting on a straight face after putting someone in a spot.
Pulling someone's leg as a group where everyone acts normal in a scenario that is funny.
Used on social networks, chat rooms and forums..at least could be!
Totally loved getting on Spook's nerves acting as if I don't know him at the bar last night. Pulled a SIS.
by far_c November 2, 2009
mugGet the SISmug.

SIS

i want you to SIS
by foonster March 8, 2010
mugGet the SISmug.

SIS

Typical abbreviation for the Saying "Slaves in shackles", Racist.
"Don't do that sis" (Don't do that, slave in shackles" "are you a sis?" (Are you a slave in shackles?)
by Educational Institutions January 6, 2022
mugGet the SISmug.

SIS

acronym for snicker inside - use instead of LOL when describing what one is actually doing when one chats/texts.
person a: I blacked out last night and lost my pants.
person b: SIS. You friend, are unpredictable.
by omniv0re December 28, 2011
mugGet the SISmug.

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